Abiogenesis and Dr. James Tour

This is the final video in a course on abiogenesis by Dr. James Tour. If the subject of the naturalistic origin of life from nonlife intrigues you, it may be good to keep in mind how unlikely something like that actually is. And yet here we are. How did we get here? If you don’t like Genesis, that question is not easy to answer and so far it has not been answered.

Regardless what you might hear in the media or the hype from origins of life researchers, no one has been able to create life from nonlife in a laboratory. They have done many amazing things with already existing life, but they have not started with nonliving chemicals and produced life. There are many reasons why this problem is difficult.

  • Life requires homochirality. Molecules do not naturally separate into left and right handed versions, but biological molecules have to for a cell to function without overheating.
  • Carbohydrates are the hardest to synthesize in a modern lab. How they could have synthesized in a prebiotic environment without lab equipment or trained technicians running that equipment is a mystery.
  • Peptides are also difficult to synthesize. Any partial success in the lab involves processes unavailable in a prebiotic environment.
  • Nucleotides may be easier until one tries to link them together, because they depend on synthesizing carbohydrates to get the ribose that joins them.
  • Lipids are sometimes said to form spontaneously. Tour said that “spontaneously” is an origin of life researcher’s code word for “I have no idea how that happened”.
  • Chiral-induced spin selectivity requires homochirality. It permits cell functions without overheating while maintaining the purity of the cell’s components.
  • RNA can not replicate enough of itself to be useful. Linking parts of it together leads to errors which make it useless. It is also unstable. The RNA World hypothesis that relies on RNA alone cannot even get started.
  • Life requires a non-random DNA code that can usefully direct the cell’s functions. Not just any random code will do. So even if you get past the other problems of synthesizing a cell from chemicals, the information problem blocks the process. How does mindless nature know what a useful code sequence could be?
  • Life is highly ordered with low entropy and high energy. How does nature produce life without violating the laws of thermodynamics?

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While writing this essay this morning I listened to one of Greg Bahnsen’s audio lectures, Amoebas, Apes and Adam that SlimJim referenced in his post Free Bahnsen Lectures: Getting Down and Dirty.

Even though Bahnsen’s lecture is some decades older than Tour’s course, Bahnsen’s chemical arguments against life coming from nonlife is in line with what Tour had to say. And Tour’s objections to abiogenesis reinforced Bahnsen’s assessment of evolution in general, not just abiogenesis, as a “grand fairy tale for adults”.

Sunday Walk 39 – Genetic Entropy

If one has a closed natural system where nothing can enter to support it from the outside, the system will run down. Any order will become disorder in a finite amount of time. Entropy is a measure of disorder.

In naturalistic or materialistic worldviews the universe we live in is supposed to be such a closed system. There is nothing outside it. Or, if there is, that supernatural stuff can’t break through the boundaries of the closed system to offer support.

In the Christian worldview not only is there an outside to the universe but that outside is powerful, willing and intelligent enough to both create the universe and make an ongoing difference to it. The material universe is not closed in this worldview although it could be hypothetically viewed as closed to study what would happen to it assuming the outside did not intervene.

For example, if we assumed nothing would stop erosion, weathering and traffic from the outside, we could ask how long the hypothetically closed system of the rock formations in the photo above would remain intact? No one doubts that there is intelligence outside this system of rock formations. Just by studying the system we are that intelligence outside it. After a study is made other people powerful and willing enough could use the findings to implement policies to preserve the formations. All of that study and preservation comes from outside this system of rock formations intervening to alter what would happen to it if those formations were left alone.

If we supposed that our universe were closed with no outside support, the main mystery would be how our universe came to be. With entropy we cannot claim that our universe had always been here to avoid addressing its origin. If our universe were infinitely old, it would have run down by now. Furthermore, any popping of ordered reality out of nothing or even out of less ordered stuff would require an explanation how that popping could increase orderliness without the assistance of some outside intelligence.

In the past it was believed that random mutations filtered through natural selection could serve as the mechanism allowing living organisms within a closed universe to evolve into ever more complex organisms without help from the outside. The change coming from random mutations would be mindlessly directed by natural selection to achieve this. R. A. Fisher even offered a mathematical proof that it would work.

However, with further study of mutation-selection the opposite is now known to happen. This perpetual motion mechanism is not what we thought it was. Even Fisher’s Theorem has been flipped by William F. Basener and John C. Sanford. The following podcast with John Sanford puts this in perspective.

James Tour & John Sanford, Genetic Entropy and Genome Degeneration

Rather than describing a means by which evolution could occur mutation-selection describes the mechanism behind genetic entropy. Without outside help, living species in a closed system not only do not evolve into super-species, they run down just like everything else does. At some point in their genome degeneration they go extinct.

Footprints